{"id":1004,"date":"2021-10-07T13:25:46","date_gmt":"2021-10-07T13:25:46","guid":{"rendered":"https:\/\/exogen.com\/the-science-behind-exogen\/"},"modified":"2022-01-13T23:38:33","modified_gmt":"2022-01-13T23:38:33","slug":"the-science-behind-exogen","status":"publish","type":"page","link":"https:\/\/www.exogen.com\/de\/the-science-behind-exogen\/","title":{"rendered":"The Science Behind EXOGEN"},"content":{"rendered":"

[vc_row row_height_percent=“0″ back_image=“182″ back_repeat=“no-repeat“ back_position=“center center“ overlay_alpha=“50″ gutter_size=“3″ column_width_percent=“100″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“210852″ row_height_pixel=“460″ back_size=“cover“ el_class=“inner-banner“ css=“.vc_custom_1634309449290{margin-top: 88px !important;margin-bottom: 44px !important;}“][vc_column column_width_percent=“100″ position_vertical=“middle“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/2″ uncode_shortcode_id=“652607″][vc_custom_heading text_color=“color-xsdn“ heading_semantic=“h1″ text_size=“fontsize-942846″ text_weight=“400″ text_transform=“uppercase“ text_height=“fontheight-667169″ uncode_shortcode_id=“811610″ text_color_type=“uncode-palette“]Die wissenschaftlichen Grundlagen von EXOGEN<\/span>[\/vc_custom_heading][vc_button size=“btn-lg“ radius=“btn-circle“ hover_fx=“outlined“ border_width=“1″ icon_position=“right“ uncode_shortcode_id=“822332″ button_color_type=“uncode-solid“ icon=“fa fa-arrow-right2″ link=“url:%2Fde%2Fcontact-an-exogen-rep%2F“ button_color_solid=“rgba(0,0,0,0.01)“ el_id=“button-transparent“]Einen EXOGEN Vertreter kontaktieren[\/vc_button][\/vc_column][vc_column width=“1\/2″][\/vc_column][\/vc_row][vc_row row_height_percent=“0″ overlay_alpha=“50″ gutter_size=“3″ column_width_percent=“100″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“122321″ css=“.vc_custom_1634309459576{margin-top: 40px !important;margin-bottom: 20px !important;}“][vc_column column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/12″ uncode_shortcode_id=“791439″][\/vc_column][vc_column column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ border_color=“color-wvjs“ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“10\/12″ uncode_shortcode_id=“377700″ css=“.vc_custom_1634614556696{border-top-width: 0px !important;border-right-width: 0px !important;border-bottom-width: 0px !important;border-left-width: 0px !important;}“ border_color_type=“uncode-palette“][vc_custom_heading text_color=“color-121277″ text_font=“font-559666″ text_size=“fontsize-242148″ text_weight=“700″ text_transform=“uppercase“ text_height=“fontheight-133340″ text_space=“fontspace-572008″ uncode_shortcode_id=“598034″ text_color_type=“uncode-palette“]Das EXOGEN Knochenheilungssystem verwendet sichere, schmerzlose, niedrigdosierte Ultraschallwellen, um die nat\u00fcrlichen Knochenheilungsprozesse des Patienten zu verst\u00e4rken.[\/vc_custom_heading][\/vc_column][vc_column width=“1\/12″][\/vc_column][\/vc_row][vc_row row_height_percent=“0″ overlay_alpha=“50″ gutter_size=“3″ column_width_percent=“100″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“162087″ css=“.vc_custom_1633601929955{margin-bottom: 30px !important;}“][vc_column width=“1\/2″][vc_row_inner row_inner_height_percent=“0″ back_color=“color-lxmt“ overlay_alpha=“50″ equal_height=“yes“ gutter_size=“0″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“504805″ row_height_pixel=“175″ back_color_type=“uncode-palette“ el_class=“science-video“ limit_content=““][vc_column_inner column_width_percent=“100″ gutter_size=“3″ expand_height=“yes“ back_image=“84″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_visibility=“yes“ mobile_width=“0″ width=“5\/12″ uncode_shortcode_id=“139484″ el_class=“video-bg-link“][vc_column_text text_color=“color-107303″ uncode_shortcode_id=“103020″ text_color_type=“uncode-palette“ el_class=“text-link“]<\/i> Watch Now<\/a>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_width_percent=“100″ position_vertical=“middle“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“7\/12″ uncode_shortcode_id=“302825″ css=“.vc_custom_1633614563286{padding-left: 40px !important;}“][vc_custom_heading heading_semantic=“h4″ text_font=“font-555555″ text_size=“h4″ text_weight=“400″ text_height=“fontheight-143712″ uncode_shortcode_id=“101912″ el_class=“video-title“]EXOGEN Wirkmechanismus[\/vc_custom_heading][vc_column_text text_color=“color-107303″ uncode_shortcode_id=“682369″ text_color_type=“uncode-palette“ el_class=“text-link“]<\/i> Watch Now<\/a>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner limit_content=““][vc_column_inner column_width_percent=“100″ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/1″ uncode_shortcode_id=“125162″ el_class=“icon-list-wrap“][vc_custom_heading text_color=“color-107303″ text_font=“font-559666″ text_size=“fontsize-950476″ text_weight=“700″ text_height=“fontheight-143712″ uncode_shortcode_id=“702822″ text_color_type=“uncode-palette“]Wirkmechanismus[\/vc_custom_heading][vc_empty_space empty_h=“2″]

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Stimulation32<\/sup><\/a><\/strong>EXOGEN sendet Ultraschallwellen durch die Haut und umgebendes Weichgewebe zur Bruchstelle des Knochens.<\/div> <\/div> <\/div> <\/div>
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Aktivierung33<\/sup><\/a><\/strong>Die Ultraschallwellen aktivieren bestimmte Zellrezeptoren und setzen so eine Reihe von Reaktionen in Gang, die als Signalkaskade bezeichnet wird.<\/div> <\/div> <\/div> <\/div>
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Hochregulierung34<\/sup><\/a><\/strong>EXOGEN Ultraschall verst\u00e4rkt die Hochregulierung der f\u00fcr die Knochenreparatur entscheidenden Prozesse.<\/div> <\/div> <\/div> <\/div> [vc_button button_color=“color-207599″ size=“btn-sm“ radius=“btn-circle“ hover_fx=“full-colored“ border_width=“0″ icon_position=“right“ uncode_shortcode_id=“997346″ button_color_type=“uncode-palette“ icon=“fa fa-arrow-right2″ link=“url:%2Fde%2Fpatient-case-studies%2F“]Patientenfallstudien anzeigen[\/vc_button][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/2″ uncode_shortcode_id=“102605″][vc_single_image media=“5279″ media_width_percent=“100″ uncode_shortcode_id=“938689″][\/vc_column][\/vc_row][vc_row row_height_percent=“0″ back_color=“color-763025″ overlay_alpha=“50″ gutter_size=“3″ column_width_percent=“100″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“855488″ back_color_type=“uncode-palette“ css=“.vc_custom_1635171897549{padding-top: 100px !important;padding-bottom: 80px !important;}“][vc_column column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/1″ uncode_shortcode_id=“102895″][vc_row_inner row_inner_height_percent=“0″ overlay_alpha=“50″ gutter_size=“3″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“694543″ el_id=“Exo_get_wrap“ limit_content=““][vc_column_inner column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/1″ uncode_shortcode_id=“301508″][vc_custom_heading text_color=“color-nhtu“ heading_semantic=“h4″ text_size=“h4″ text_weight=“400″ text_height=“fontheight-143712″ uncode_shortcode_id=“190673″ text_color_type=“uncode-palette“ el_class=“bottom-sup“]EXOGEN wurde in mehreren klinischen Studien der Evidenzklassen I und II untersucht*1-3,5,13-31<\/a><\/sup>[\/vc_custom_heading][vc_empty_space empty_h=“1″][vc_raw_html el_class=“list-step science-step“]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[\/vc_raw_html][vc_empty_space empty_h=“2″][\/vc_column_inner][\/vc_row_inner][vc_row_inner row_inner_height_percent=“0″ overlay_alpha=“50″ gutter_size=“3″ border_style=“solid“ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“124578″ css=“.vc_custom_1635172221351{border-top-width: 0px !important;border-right-width: 0px !important;border-bottom-width: 0px !important;border-left-width: 0px !important;}“ border_color_type=“uncode-solid“ border_color_solid=“#979797″ limit_content=““][vc_column_inner column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/12″ uncode_shortcode_id=“109597″][\/vc_column_inner][vc_column_inner column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“10\/12″ uncode_shortcode_id=“150387″][vc_column_text border_style=“solid“ uncode_shortcode_id=“125980″ css=“.vc_custom_1639821062256{border-top-width: 1px !important;border-right-width: 0px !important;border-bottom-width: 0px !important;border-left-width: 0px !important;padding-top: 30px !important;}“ border_color_type=“uncode-solid“ el_class=“text-twenty“ border_color_solid=“#bfbfbf“]*Diese Studien, die die Nachweislage f\u00fcr den Knochenstimulator EXOGEN widerspiegeln, beinhalten auch Evaluierungen von zulassungs\u00fcberschreitenden Anwendungen. Die Zuordnung der Evidenzklassen erfolgte auf der Grundlage des aktualisierten Evidenzbewertungssystems der Oxford-Kriterien.<\/em>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=“1\/12″][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=“0″ overlay_alpha=“50″ gutter_size=“3″ column_width_percent=“100″ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“543000″ back_color_type=“uncode-gradient“ back_color_gradient=“{„css„:„background: linear-gradient(to right , rgb(68, 29, 77) , rgb(176, 85, 29) 100%);„,„sliders„:`{`{„color„:„rgb(68, 29, 77)„,„position„:0},{„color„:„rgb(176, 85, 29)„,„position„:100}`}`,„type„:„linear„,„direction„:„left„}“ css=“.vc_custom_1633605125010{padding-top: 100px !important;padding-bottom: 80px !important;}“][vc_column column_width_percent=“100″ align_horizontal=“align_center“ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/1″ uncode_shortcode_id=“102895″][vc_row_inner limit_content=““][vc_column_inner column_width_percent=“100″ gutter_size=“3″ overlay_alpha=“50″ shift_x=“0″ shift_y=“0″ shift_y_down=“0″ z_index=“0″ medium_width=“0″ mobile_width=“0″ width=“1\/1″ uncode_shortcode_id=“620789″][vc_custom_heading text_color=“color-xsdn“ heading_semantic=“h3″ text_font=“font-559666″ text_size=“fontsize-950476″ text_weight=“300″ text_height=“fontheight-143712″ uncode_shortcode_id=“130210″ text_color_type=“uncode-palette“]Indikationen[\/vc_custom_heading][vc_column_text text_color=“color-xsdn“ uncode_shortcode_id=“534190″ text_color_type=“uncode-palette“]EXOGEN ist f\u00fcr die nicht-invasive Behandlung oss\u00e4rer Defekte (mit Ausnahme der Wirbel und des Sch\u00e4dels) sowie zur Behandlung von verz\u00f6gert ausheilenden Br\u00fcchen, Pseudarthrosen\u2020<\/sup>, Belastungsbr\u00fcchen und Gelenkfusionen indiziert. EXOGEN ist au\u00dferdem f\u00fcr eine beschleunigte Ausheilung frischer Frakturen, zur Wiederherstellung nach Osteotomie, zur Wiederherstellung nach Knochentransportverfahren und zur Wiederherstellung nach Distraktionsosteogeneseverfahren indiziert.<\/p>\n

Es gibt keine bekannten Gegenanzeigen f\u00fcr das EXOGEN-System. Es wurden keine Untersuchungen zu Sicherheit und Wirksamkeit bei Personen mit unreifem Skelett, bei schwangeren oder stillenden Frauen, bei Patienten mit Herzschrittmachern, bei knochenkrebsbedingten Frakturen oder bei Patienten mit Durchblutungs- oder Blutgerinnungsst\u00f6rungen durchgef\u00fchrt. Manche Patienten k\u00f6nnen empfindlich auf das Ultraschallgel reagieren.<\/p>\n

Vollst\u00e4ndige Informationen zur Verordnung finden Sie auf der Produktetikettierung, unter https:\/\/www.exogen.com\/<\/a> oder telefonisch mit einem Anruf beim Bioventus Kundenservice.<\/p>\n

\u2020<\/sup>Eine schlecht heilende Knochenfraktur liegt vor, wenn die Bruchstelle keine sichtbaren Anzeichen eines fortschreitenden Heilungsprozesses aufweist.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=“0″ overlay_alpha=“50″ gutter_size=“3″ column_width_percent=“100″ border_color=“color-gyho“ border_style=“solid“ shift_y=“0″ z_index=“0″ uncode_shortcode_id=“171023″ css=“.vc_custom_1642014068309{margin-top: 10px !important;margin-bottom: 0px !important;border-top-width: 0px !important;}“ border_color_type=“uncode-palette“ shape_dividers=““][vc_column width=“1\/1″][vc_column_text text_lead=“small“ uncode_shortcode_id=“126520″]*The clinical relevance of in vivo findings is unknown[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

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