EXOGEN has demonstrated proven clinical effectiveness2-4 and 91% treatment compliance.5 Using low-intensity pulsed ultrasound (LIPUS) technology, EXOGEN activates a biological healing response at the molecular level.6 EXOGEN makes tracking treatment compliance convenient for your patients and verifiable for you with a built-in treatment tracking calendar.

  • #1 prescribed bone healing system globally 6
  • 20-minute daily treatment
  • 38% faster healing of fresh fractures2,3
  • 86% healing of nonunions4
  • High level of treatment clinically proven treatment compliance: 91%5
  • Over double the number of Level 1,2, and 3 clinical studies than all competitors combined..1

Successful bone healing depends on both proven effectiveness and treatment compliance.
EXOGEN delivers both.

Indications for Use

EXOGEN is indicated for the non-invasive treatment of osseous defects (excluding vertebra and skull) that includes the treatment of delayed unions, nonunions, stress fractures and joint fusion. EXOGEN is also indicated for the acceleration of fresh fracture heal time, repair following osteotomy, repair in bone transport procedures and repair in distraction osteogenesis procedures.

There are no known contraindications for the EXOGEN device. Safety and effectiveness have not been established for individuals lacking skeletal maturity, pregnant or nursing women, patients with cardiac pacemakers, on fractures due to bone cancer, or on patients with poor blood circulation or clotting problems. Some patients may be sensitive to the ultrasound gel.

†A nonunion is considered to be established when the fracture site shows no visibly progressive signs of healing.

EXOGEN Personalized Patient Services

Your Goals Are Our Goals
EXOGEN Ultrasound Bone Healing System offers a full suite of support tools to help achieve the goals of your practice and your patients.

  • Convenient patient resources
  • High treatment compliance40
  • Improved clinical outcomes2-4
  • Maximized patient satisfaction

Mechanism of Action

1 Stimulation
EXOGEN sends ultrasound waves through the skin and soft tissue to the fracture.

2 Activation
EXOGEN ultrasound activates cell surface mechanoreceptors called integrins, initiating an intracellular cascade that leads to upregulation.

3 Upregulation
EXOGEN ultrasound increases upregulation of genes and expression proteins and growth factors critical to bone healing.

Proven Effectiveness

EXOGEN has over double the number of Level 1, 2 and 3 clinical studies than all competitors combined.1
EXOGEN has the most clinical evidence for efficacy of any licenced bone healing device worldwide.6

 *These studies, which reflect the body of evidence of the bone stimulator EXOGEN, include evaluations of applications outside the approved label. Assignment of evidence levels was based on the updated level of evidence rating system in the Journal of Bone and Joint Surgery. 2015;97(1):1-2.

EXOGEN’s Full Suite of Support Tools

20-Minute Daily Treatments
With treatments lasting just 20 minutes, EXOGEN fits easily into the patient’s daily routine.

Treatment Tracking Calendar
EXOGEN’s built in treatment tracking calendar records completed and missed treatments, making tracking treatment compliance convenient for patients and verifiable for physicians.

LMT Surgical Customer Service
LMT Surgical Customer Service is available on 1300 880 155 to answer your patients' questions and help them stay consistent with their EXOGEN treatment.

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