Patient Case Studies

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Initial History

  • Right reverse obliquity subtrochanteric femur fracture

11 Months Post-injury

  • CT scan shows persistent hypertronphic nonunion
  • Hardware and fracture stable
  • EXOGEN prescribed


  • Post-op locked cephalomedullary nailing
  • Persistent pain/lack of healing
  • Underwent nail dynamization at 9 months post-injury

3 Months of EXOGEN Use, 14 Months Post-injury

  • Nonunion healed
  • Symptoms resolved
  • Additional surgery avoided

3 Months

  • No progression of healing
  • Nonunoin diagnosis
  • EXOGEN prescribed
  • Remained in long-leg cast

7 Months

  • Nonunion healed
  • Addiotional bone healing evident
  • Surgery avoided

5 Months

  • Progressed to short-legged walking cast
  • Significant bony healing

3 Months Post-Op

  • No progression with healing, nonunion diagnosis
  • Screw from prior surgery in bending
  • EXOGEN prescribed
  • Boot with weight bearing continued

8 Months Post-Op

  • Patient returned to football

7 Months Post-Op, 17 Weeks of EXOGEN Use

  • Complete union noted 17 weeks after initiating EXOGEN
  • Patient asymptomatic
  • Additional surgery avoided

Summary of Indications for Use
EXOGEN is indicated for the non-invasive treatment of osseous defects (excluding vertebra and skull) that includes the treatment of delayed unions, nonunions,* stress fractures and joint fusion. EXOGEN is also indicated for the acceleration of fresh fracture heal time, repair following osteotomy, repair in bone transport procedures and repair in distraction osteogenesis procedures.

There are no known contraindications for the EXOGEN device. Safety and effectiveness have not been established for individuals lacking skeletal maturity, pregnant or nursing women, patients with cardiac pacemakers, on fractures due to bone cancer, or on patients with poor blood circulation or clotting problems. Some patients may be sensitive to the ultrasound gel.

Full prescribing information can be found in product labeling, at, or by calling Bioventus Customer Service.

*A nonunion is considered to be established when the fracture site shows no visibly progressive signs of healing.