EXOGEN has demonstrated proven clinical effectiveness2-4 and 91%12 treatment compliance. Using low-intensity pulsed ultrasound (LIPUS) technology, EXOGEN activates a biological healing response at the molecular level.6 EXOGEN makes treatment compliance tracking convenient for your patients and verifiable for you with a built-in treatment tracking calendar.
- #1 prescribed bone healing system7
- 20-minute daily treatment
- 38% faster healing of indicated* fresh fractures2,3
- 86% healing of nonunions†4
- Clinically proven high level of treatment: 91%12
- Over double the number of Level 1,2, and 3 clinical studies than all competitors combined.1
Successful bone healing depends on both proven effectiveness and treatment compliance. EXOGEN delivers both.
Indications for Use
EXOGEN is indicated for the non-invasive treatment of osseous defects (excluding vertebra and skull) that includes the treatment of delayed unions, nonunions†, stress fractures and joint fusion. EXOGEN is also indicated for the acceleration of fresh fracture heal time, repair following osteotomy, repair in bone transport procedures and repair in distraction osteogenesis procedures.
There are no known contraindications for the EXOGEN device. Safety and effectiveness have not been established for individuals lacking skeletal maturity, pregnant or nursing women, patients with cardiac pacemakers, on fractures due to bone cancer, or on patients with poor blood circulation or clotting problems. Some patients may be sensitive to the ultrasound gel.
† A nonunion is considered to be established when the fracture site shows no visibly progressive signs of healing.
Mechanism of Action
EXOGEN sends ultrasound waves through the skin and soft tissue to the fracture.
EXOGEN ultrasound activates cell surface mechanoreceptors called integrins, initiating an intracellular cascade that leads to upregulation.
EXOGEN ultrasound increases upregulation of genes and expression proteins and growth factors critical to bone healing.
EXOGEN’s Full Suite of Support Tools
20-Minute Daily Treatments
With treatments lasting just 20 minutes, EXOGEN fits easily into the patient’s daily routine.
Treatment Tracking Calendar
EXOGEN’s built in treatment tracking calendar tracks completed and missed treatments, making treatment compliance tracking convenient for patients and verifiable for physicians.